Investigator 24Plex QS
Definition
Qiagen 26-plex STR kit with Quality Sensor (IPC) and covering 24 STR loci plus DYS391 and Amelogenin. GO! variant uses increased cycles for challenging samples.
- Manufacturer
- Qiagen
- Loci covered
- 24 STR loci plus DYS391 and Amelogenin
- Quality control
- Built-in Quality Sensor (internal PCR control)
- Sensitive variant
- GO!, uses increased cycles for challenging samples
Common questions
What does the Quality Sensor (IPC) detect?+
It monitors amplification of an internal control alongside the sample, flagging PCR inhibition or degraded template so a no-result can be distinguished from a genuine assay failure.
When would a lab choose the GO! variant?+
For degraded, low-quantity or otherwise challenging samples, where the increased cycle number improves sensitivity, though this comes at some cost to stutter and allele-balance interpretation.
Related terms
- Allelic Drop-Out
- Failure of one allele of a heterozygous locus to amplify detectably, a stochastic effect of low-template amplification where sampling of limited template...
- ESSplex SE QS
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- GlobalFiler
- Applied Biosystems 25-plex STR kit covering 24 STR loci plus Amelogenin, compatible with both CODIS 20 and ESS17 requirements.
- Haematin
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- Humic Acid
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- Identifiler Plus
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- IPC (Internal PCR Control)
- A non-forensic DNA sequence spiked into the PCR reaction at fixed concentration; a shift in IPC Ct value relative to the expected...
- Low-Copy-Number (LCN) PCR
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- PowerPlex Fusion 6C
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- Probabilistic Genotyping
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