Tamm-Horsfall protein (uromodulin)
Definition
The most abundant urinary protein in healthy individuals, produced exclusively by epithelial cells of the loop of Henle and excreted into urine. Its kidney-specific origin makes it the target of RSID-Urine.
Related terms
- Creatinine
- A breakdown product of creatine phosphate in muscle. It is filtered by the kidneys and excreted in urine at relatively constant rates,...
- Dermcidin
- A small antimicrobial peptide expressed constitutively in eccrine sweat glands and secreted in sweat. Proposed as a candidate sweat marker in research...
- Eccrine glands
- The primary sweat glands distributed across most body surfaces, producing a watery secretion mainly of water, sodium chloride, and trace amounts of...
- RSID-Urine
- Rapid Stain Identification of Urine. An immunochromatographic lateral-flow assay that detects Tamm-Horsfall protein in biological extracts, providing a highly specific confirmatory test...
- Urea
- A product of protein catabolism excreted primarily in urine, present at 200 to 400 mmol per litre. Also present at lower concentrations...
Explained in
- Urine and Sweat IdentificationThe most abundant urinary protein in healthy individuals, produced exclusively by epithelial cells of the loop of Henle and excreted into urine. Its kidney-spe...