PSA / P30
Definition
Prostate-specific antigen, also called p30, is a protein targeted by some assays used in forensic semen-related examination. Its interpretation depends on the validated assay, specimen and other findings; detecting the marker alone does not identify a donor or establish an activity.
Related terms
- Azoospermia
- The absence of spermatozoa from ejaculated semen, resulting from obstructive causes (vasectomy, ductal blockage) or non-obstructive causes (testicular failure). Azoospermic semen contains...
- ABAcard P30
- A lateral-flow immunochromatographic strip manufactured by Abacus Diagnostics and validated by the Scientific Working Group for DNA Analysis Methods (SWGDAM) for forensic...
- Activity Proposition
- A stated explanation about actions or transfer, distinct from whose DNA is present. An activity question concerns actions, such as direct contact...
- Differential Extraction
- A DNA extraction method used for sexual assault evidence that separates sperm cells from epithelial cells before cell lysis, yielding two DNA...
- Lateral-Flow Immunochromatographic Assay
- A rapid, single-use immunoassay format in which sample extract migrates along a nitrocellulose membrane past a detection zone loaded with antigen-specific antibody...
- RSID-Saliva
- Rapid Stain Identification of Saliva. An immunochromatographic lateral-flow assay using monoclonal antibodies specific to human salivary amylase. More specific than Phadebas, with...
- Salivary Alpha-Amylase
- An enzyme (EC 3.2.1.1) secreted by the parotid, submandibular, and sublingual glands. Digests starch and is present in saliva at concentrations of...
- Substrate Comparison
- A sample used to investigate relevant background on an item, distinct from process blanks. Material from an appropriate part of an item...
Explained in these topics
- Immunological Identification of Semen and SalivaProstate-specific antigen, a kallikrein-family serine protease secreted by prostatic epithelium. Present in seminal plasma at 0.5 to 2 mg/mL. The standard conf...
- Semen, Saliva and Other Body Fluids as EvidenceA protein associated strongly with prostatic secretions, interpreted with assay-specific limits.