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SWGDRUG Category C

Definition

The lowest tier in the Scientific Working Group for the Analysis of Seized Drugs classification. Category C methods (including colour tests, microcrystal tests, and fluorescence microscopy) have the lowest analytical discriminating power and cannot be used alone for drug identification. At least one Category A method is required for a confirmatory identification.

Working group
SWGDRUG
Tier
Lowest of the category system
Example methods
Colour tests, microcrystal tests, fluorescence microscopy
Limitation
Cannot confirm identification alone
Requirement
At least one Category A method needed for confirmation

Common questions

Why can't a Category C method confirm a drug's identity on its own?+

Category C tests such as colour or microcrystal tests respond to a class of compounds rather than a single specific substance, so a positive result narrows the possibilities without uniquely identifying the drug. A structurally specific Category A technique, such as mass spectrometry, is needed to rule out other compounds giving the same presumptive reaction.

What role do Category C tests still play if they can't confirm identity?+

They are used as rapid, low-cost screening tools at the scene or early in the lab workflow to triage samples and decide priorities, before the sample goes on to a confirmatory Category A method for the final reportable identification.

Related terms

Cobalt Thiocyanate
Co(SCN)2 in aqueous solution; the active reagent in the Scott test for cocaine. Cocaine forms a lipophilic blue complex with cobalt thiocyanate...
Duquenois-Levine Test
A three-reagent presumptive test for cannabinoids: vanillin + acetaldehyde in ethanol (Reagent 1), concentrated hydrochloric acid (Reagent 2), and chloroform partition (Reagent...
False Positive (Presumptive Test)
A positive colour response from a compound that is not the targeted controlled substance. Common sources include diphenhydramine (Marquis orange, Scott blue),...
Mandelin Reagent
Ammonium metavanadate (NH4VO3) in concentrated sulphuric acid. Useful for amphetamines (orange-red), MDMA (dark blue-black) and cocaine (yellow-orange). The Mandelin-Marquis panel is recommended...
Marquis Reagent
A presumptive drug test reagent consisting of formaldehyde in concentrated sulphuric acid, first described by Edmund Marquis in 1896. It produces characteristic...
Mecke Reagent
Selenious acid (H2SeO3) dissolved in concentrated sulphuric acid. More selective than Marquis for the opioid alkaloid skeleton; morphine and heroin give a...
NIK Polytesting
A field drug testing approach using the NIK Public Safety sealed ampoule system, where multiple colour tests are run sequentially on the...
Scott Test
A three-step cobalt thiocyanate presumptive test for cocaine and its salts. Step 1: cobalt thiocyanate reagent (blue in aqueous phase). Step 2:...
Simon's Test
A presumptive test that uses sodium nitroprusside and sodium carbonate to detect secondary amines (N-methyl group). Methamphetamine and MDMA (secondary amines) give...

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