Se Gene / Se428
Definition
The original notation for the secretor locus (Se for secretor, se or FUT2*428A for the non-secretor null allele carrying a nonsense mutation at codon 428). The most common non-secretor allele in European and Asian populations.
Related terms
- Blood-Group Substance
- Soluble ABO antigens (A substance, B substance, H substance) present in the body fluids of secretors. Chemically distinct from the glycolipid-bound cell-surface...
- FUT2 Gene
- The Fucosyltransferase 2 gene on chromosome 19q13, encoding the alpha-1,2-fucosyltransferase enzyme responsible for adding fucose to type-1 chain precursors in secretory tissues...
- Inhibition Index
- A quantitative measure of PCR inhibitor burden in a DNA extract, derived from the Ct shift of an internal positive control (IPC)...
- Non-Secretor
- An individual homozygous for non-functional FUT2 alleles who produces no H, A, or B antigen in saliva, semen, or other exocrine secretions,...
- Secretor
- An individual whose ABO blood group antigens are expressed on red blood cells and also released into body fluids such as saliva,...
Explained in
- Secretor Status and Its Forensic ValueThe original notation for the secretor locus (Se for secretor, se or FUT2*428A for the non-secretor null allele carrying a nonsense mutation at codon 428). The...