FUT2 gene
Definition
The Fucosyltransferase 2 gene on chromosome 19q13, encoding the alpha-1,2-fucosyltransferase enzyme responsible for adding fucose to type-1 chain precursors in secretory tissues to generate H substance in body fluids.
Related terms
- Blood-group substance
- Soluble ABO antigens (A substance, B substance, H substance) present in the body fluids of secretors. Chemically distinct from the glycolipid-bound cell-surface...
- Inhibition index
- A quantitative measure of PCR inhibitor burden in a DNA extract, derived from the Ct shift of an internal positive control (IPC)...
- Non-secretor
- An individual homozygous for non-functional FUT2 alleles who produces no H, A, or B antigen in saliva, semen, or other exocrine secretions,...
- Se gene / Se428
- The original notation for the secretor locus (Se for secretor, se or FUT2*428A for the non-secretor null allele carrying a nonsense mutation...
- Secretor
- Person who secretes water-soluble ABH blood-group substances into saliva, semen and other body fluids. About 80% of the Indian population are secretors;...
Explained in
- Secretor Status and Its Forensic ValueThe Fucosyltransferase 2 gene on chromosome 19q13, encoding the alpha-1,2-fucosyltransferase enzyme responsible for adding fucose to type-1 chain precursors in...