NIST SRM (Standard Reference Material)
Definition
A reference material issued by the US National Institute of Standards and Technology (NIST) in Gaithersburg, Maryland, whose property values are established using primary measurement methods and are traceable to the SI through NIST's own calibration capability; the highest metrological authority for reference materials in the US system.
Related terms
- Certified Reference Material (CRM)
- A sample with one or more analyte concentrations established by an accredited body and traceable to a national metrology institute. NIST SRM...
- Internal Standard (IS)
- A compound chemically near-identical to the analyte, often a deuterated isotopologue (d3-morphine, d5-EDDP, d5-alprazolam, pyrene-d10), spiked into every sample at a known...
- ISO 17034
- The international standard specifying general requirements for the competence of reference material producers; an ISO 17034-accredited producer has demonstrated the technical competence...
- Limit of Detection (LOD)
- The lowest concentration of analyte that produces a signal reliably distinguishable from the instrument noise, conventionally three times the standard deviation of...
- Limit of Quantification (LOQ)
- The smallest concentration that can be quantified with acceptable precision and accuracy, typically corresponding to a signal-to-noise ratio of 10:1 or an...
- Linearity
- The range of analyte concentrations over which an analytical method produces instrument responses that are proportional to concentration (the calibration curve is...
- Measurement Uncertainty (MU)
- A quantified parameter associated with a result that characterises the dispersion of values reasonably attributable to the measurand. Estimated by the GUM...
- Metrological Traceability
- A property of a measurement result whereby the result can be related to a reference (ultimately the SI system of units) through...
- System Suitability Test
- A pre-run check in which a standard mixture is injected into the analytical instrument and key parameters (retention times, peak widths, signal-to-noise...
Explained in
- Reference Standards, Certified Reference Materials and the Quantification BaselineA reference material issued by the US National Institute of Standards and Technology (NIST) in Gaithersburg, Maryland, whose property values are established us...