Limit of detection (LOD) and quantitation (LOQ)
LOD is the lowest concentration at which the signal-to-noise ratio is 3:1; LOQ is where it is 10:1. LC-MS/MS LOQs for drugs in biological matrices typically sit between 0.1 and 1 ng/mL.
LOD is the lowest concentration at which the signal-to-noise ratio is 3:1; LOQ is where it is 10:1. LC-MS/MS LOQs for drugs in biological matrices typically sit between 0.1 and 1 ng/mL.
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