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Galena (PbS)

Definition

Lead(II) sulfide: the principal ore of lead, a grey-black metallic mineral used as the traditional pigment in kohl eye cosmetics for thousands of years. Contains 86.6% lead by mass in the pure mineral form. Natural galena deposits are associated with antimony-bearing minerals (stibnite, Sb2S3), giving traditional galena kohl dual lead and antimony toxicity.

Related terms

Ammoniated Mercury
A mercury-ammonia complex (mercuric chloride-ammonia, HgNH2Cl) historically used as a skin-lightening active ingredient. Inhibits melanogenesis by binding to tyrosinase's active-site cysteine. Causes...
EU Regulation 1223/2009
The EU Cosmetics Regulation: the primary legal framework governing cosmetics marketed in the EU. Annex II (prohibited substances) lists lead (Entry 209),...
Formaldehyde-Releasing Preservative (FRP)
A preservative that slowly releases formaldehyde as its antimicrobial active ingredient. The five principal FRPs in cosmetics are quaternium-15, DMDM hydantoin, imidazolidinyl...
Kohl (Kajal, Surma, Al-Kohl)
A dark powder applied to the eyes as a cosmetic in South Asian and Middle Eastern cultural traditions. Traditional mineral kohl is...
MoCRA 2022
Modernization of Cosmetics Regulation Act 2022 (US), signed into law December 2022. Requires cosmetic-facility registration with FDA, product listing, safety substantiation, adverse-event...
Nash Reagent Method
The EU reference colorimetric method for free formaldehyde in cosmetics: formaldehyde reacts with ammonium acetate and acetylacetone to produce the yellow 3,5-diacetyl-1,4-dihydrolutidine...
RAPEX / Safety Gate
The EU rapid alert system for dangerous non-food consumer products, including cosmetics. Analogous to RASFF for food. Member states notify dangerous products;...
Rhodamine B
A xanthene dye (C28H31ClN2O3, MW 479.0) with brilliant pink fluorescence, listed on the EU REACH SVHC candidate list as a suspected carcinogen...
Tyrosinase Inhibition
The mechanism by which mercury compounds and some other skin-lightening agents achieve depigmentation: mercury binds to the sulphydryl (cysteine) group at the...

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