Formaldehyde-Releasing Preservative (FRP)

Related terms

Ammoniated Mercury

A mercury-ammonia complex (mercuric chloride-ammonia, HgNH2Cl) historically used as a skin-lightening active ingredient. Inhibits melanogenesis by binding to tyrosinase's active-site cysteine. Causes...

EU Regulation 1223/2009

The EU Cosmetics Regulation: the primary legal framework governing cosmetics marketed in the EU. Annex II (prohibited substances) lists lead (Entry 209),...

Galena (PbS)

Lead(II) sulfide: the principal ore of lead, a grey-black metallic mineral used as the traditional pigment in kohl eye cosmetics for thousands...

Kohl (Kajal, Surma, Al-Kohl)

A dark powder applied to the eyes as a cosmetic in South Asian and Middle Eastern cultural traditions. Traditional mineral kohl is...

MoCRA 2022

Modernization of Cosmetics Regulation Act 2022 (US), signed into law December 2022. Requires cosmetic-facility registration with FDA, product listing, safety substantiation, adverse-event...

Nash Reagent Method

The EU reference colorimetric method for free formaldehyde in cosmetics: formaldehyde reacts with ammonium acetate and acetylacetone to produce the yellow 3,5-diacetyl-1,4-dihydrolutidine...

RAPEX / Safety Gate

The EU rapid alert system for dangerous non-food consumer products, including cosmetics. Analogous to RASFF for food. Member states notify dangerous products;...

Rhodamine B

A xanthene dye (C28H31ClN2O3, MW 479.0) with brilliant pink fluorescence, listed on the EU REACH SVHC candidate list as a suspected carcinogen...

Tyrosinase Inhibition

The mechanism by which mercury compounds and some other skin-lightening agents achieve depigmentation: mercury binds to the sulphydryl (cysteine) group at the...

Explained in

• Cosmetics Chemistry: Heavy Metals, Banned Colourants and Formaldehyde ReleaseA preservative that slowly releases formaldehyde as its antimicrobial active ingredient. The five principal FRPs in cosmetics are quaternium-15, DMDM hydantoin...