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CODIS (Combined DNA Index System)

Definition

The FBI-managed software architecture for the US national forensic DNA database, operating through a three-tier structure of local (LDIS), state (SDIS), and national (NDIS) index systems.

Management
Operated by the Federal Bureau of Investigation (FBI)
Structure
Three-tier system: local (LDIS), state (SDIS), and national (NDIS) index systems
Primary use
Forensic DNA database for profile matching in criminal investigations

Common questions

What is CODIS and who manages it?+

CODIS is the Combined DNA Index System, the FBI-managed software architecture that runs the US national forensic DNA database. It operates through a three-tier structure: local databases (LDIS), state databases (SDIS), and the national database (NDIS) for profile matching and investigation support.

What is the CODIS core locus set?+

The CODIS core locus set defines the minimum DNA loci required for a profile to be uploaded to the National DNA Index System (NDIS). This standardized set ensures consistency across jurisdictions and enables reliable matching between profiles in the database.

How does CODIS help forensic investigations?+

By maintaining DNA profiles from crime scenes and convicted offenders across multiple jurisdictional levels, CODIS allows investigators to search for matches that may link crimes together or identify suspects. The tiered structure lets local and state agencies query their own databases before escalating to the national level.

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The uppermost tier of the US CODIS architecture, holding profiles contributed by all US federal and state DNA database programs. As of...
NDNAD
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S and Marper V. UK (2008)
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