VNTR (Variable Number Tandem Repeat)
Definition
A tandemly repeated genomic sequence with a longer repeat unit (typically 10, 60 bp) than an STR. VNTRs were used in the first-generation RFLP DNA fingerprinting systems of the 1980s and early 1990s before PCR-based STR typing became practical.
Related terms
- Amelogenin
- A gene on both the X and Y chromosomes used for sex determination in forensic STR kits. The X-allele amplicon is approximately...
- CODIS
- The FBI's Combined DNA Index System, the US national STR-based forensic DNA database. Contains profiles from convicted offenders, arrestees, and unidentified crime-scene...
- ESS (European Standard Set)
- The set of STR loci required for profiles entered into EU national databases participating in Prüm cross-border DNA exchange. Currently aligned with...
- Heterozygosity
- The proportion of individuals in a population who carry two different alleles at a locus. A locus with high heterozygosity is more...
- STR (Short Tandem Repeat)
- A genomic locus where a 2, 7 base-pair unit is repeated in tandem a variable number of times between individuals. The variation...
Explained in
- Polymorphism, Heredity and the Markers that Identify a PersonA tandemly repeated genomic sequence with a longer repeat unit (typically 10, 60 bp) than an STR. VNTRs were used in the first-generation RFLP DNA fingerprinti...