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Reagent Blank

Definition

A control without an intended specimen carried through relevant processing steps. Controls examine relevant background from devices, reagents or processing. Their selection should match the contamination pathways and stages being assessed.

Context
Contamination controls

For example, processing a reagent blank can reveal background introduced by reagents or preparation rather than material intentionally sampled from an exhibit.

A clean control does not rule out every earlier contamination event. A positive control finding needs investigation rather than an automatic conclusion about every exhibit.

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