PowerPlex Y23
Definition
Commercial Y-STR multiplex kit (Promega Corporation) amplifying 23 loci, overlapping substantially with Yfiler Plus. The 20-locus YHRD core set is covered by both kits, enabling cross-database comparison.
- Manufacturer
- Promega Corporation
- Loci amplified
- 23 Y-STR loci
- Core overlap
- 20-locus YHRD minimal haplotype set
- Comparable kit
- Yfiler Plus (Thermo Fisher)
Common questions
Why does YHRD core-set overlap matter?+
Because both PowerPlex Y23 and Yfiler Plus type the same 20 core loci, a haplotype generated on either kit can be searched against the same YHRD database entries, letting labs compare results across instrument platforms and vendors without re-typing samples.
Does PowerPlex Y23 replace autosomal STR kits?+
No. Y-STR kits type only the male-specific Y chromosome and are used for lineage tracing or male-fraction analysis in mixtures, not for individual identification, since all paternally related males share the same Y-STR profile.
Related terms
- Argus X-12 QS
- Investigator Argus X-12 QS (Qiagen), the most widely validated commercial X-STR multiplex kit. Amplifies 12 loci in four linkage groups; used with...
- X-STR Linkage Group
- A cluster of X-STR loci that are physically linked on the X chromosome and transmitted as a haplotype block in females. Loci...
- Y-STR Haplotype
- The combination of allele values across all Y-chromosome STR loci typed in a single analysis. Reported as a string of allele values...
- Yfiler Plus
- Commercial Y-STR multiplex kit (ThermoFisher Scientific) amplifying 27 loci in a single PCR reaction. Current standard for Y-STR casework in many US,...
- YHRD
- Y-Chromosome STR Haplotype Reference Database, maintained at the Charité Berlin and freely accessible at yhrd.org. Contains over 340,000 haplotypes from 124 countries....