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Positivity Threshold

Definition

The minimum number of frustules per gram of tissue or per slide that a laboratory uses to declare a result positive. No universal standard exists; threshold proposals in the literature range widely, and different thresholds applied to the same case can produce opposite conclusions.

Related terms

Background Contamination
Diatom frustules introduced into a sample from sources other than the victim's own body: tap water, laboratory air, unclean glassware, reagents, and...
Diatom Density
The number of frustules per unit volume of water in the drowning environment. Low-density environments (pools, tap water, diatom-poor rivers) cannot deliver...
False Negative
A negative result from a preparation in which ante-mortem drowning actually did occur. Causes include low diatom density in the drowning water,...
False Positive
A test result that indicates the presence of a target analyte when it is absent. In forensic serology this may mean incorrectly...
Standardisation
The production of a validated, peer-reviewed protocol that specifies every variable in the test: acid type and concentration, digestion time and temperature,...

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