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Standardisation

Definition

The production of a validated, peer-reviewed protocol that specifies every variable in the test: acid type and concentration, digestion time and temperature, filtration conditions, slide preparation, counting method, and reporting format. The current absence of a universally adopted standard is the most frequently cited systemic weakness of the method.

Related terms

Background contamination
Diatom frustules introduced into a sample from sources other than the victim's own body: tap water, laboratory air, unclean glassware, reagents, and...
Diatom density
The number of frustules per unit volume of water in the drowning environment. Low-density environments (pools, tap water, diatom-poor rivers) cannot deliver...
False negative
A negative result from a preparation in which ante-mortem drowning actually did occur. Causes include low diatom density in the drowning water,...
False positive
A test result indicating diatoms consistent with ante-mortem aspiration in an organ sample when the diatoms actually arrived by contamination, post-mortem diffusion,...
Positivity threshold
The minimum number of frustules per gram of tissue or per slide that a laboratory uses to declare a result positive. No...

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