Nuclear DNA (nDNA)
Definition
The genomic DNA housed in the cell nucleus, packaged as 46 chromosomes in human somatic cells. The primary target for STR profiling and most forensic DNA typing. Diploid: approximately 6.4 billion base pairs per somatic cell.
Related terms
- Chromatin
- The complex of nuclear DNA wound around histone proteins in the nucleus. In forensic DNA extraction, chromatin must be disrupted to release...
- Cytoskeleton
- The protein scaffold within eukaryotic cells, composed of actin microfilaments, tubulin microtubules, and intermediate filaments such as keratin. Provides cell shape and...
- Eukaryote
- An organism whose cells contain a membrane-bound nucleus and other membrane-enclosed organelles. Humans, animals, plants, and fungi are eukaryotes. Most biological evidence...
- Mitochondrial DNA (mtDNA)
- DNA located in mitochondria rather than the cell nucleus. Present in hundreds to thousands of copies per cell, making it recoverable from...
- Prokaryote
- An organism whose cells lack a membrane-bound nucleus and organelles. Bacteria and archaea are prokaryotes. They are relevant to forensic biology in...
Explained in
- Cell Structure and Organelles for Forensic ScientistsThe genomic DNA housed in the cell nucleus, packaged as 46 chromosomes in human somatic cells. The primary target for STR profiling and most forensic DNA typin...