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Mitochondrial DNA (mtDNA)

Definition

DNA located in mitochondria rather than the cell nucleus. Present in hundreds to thousands of copies per cell, making it recoverable from highly degraded samples including processed bone, dried tissue, and heat-treated products. Maternally inherited, so it identifies species and maternal lineage but cannot distinguish between individuals from the same maternal line.

Related terms

ABO Blood Group System
Classification of red blood cells by the presence or absence of A and B antigens on the cell membrane, determined by alleles...
Chain of Custody
The documented chronological record of who collected, handled, transferred, and examined a piece of evidence. For digital evidence, chain of custody includes...
Degradation
The breakdown of DNA by enzymatic, chemical, or physical processes after biological material is deposited. Degradation produces fragmented DNA that may not...
Medullary Index
The ratio of the medulla diameter to the total hair shaft diameter. In companion animal hair identification, a medullary index above 0.5...
Short Tandem Repeat (STR)
Short repetitive DNA sequences scattered throughout the genome, with the number of repeats varying between individuals at each locus. DNA profiling compares...
Short Tandem Repeat (STR) Profiling
The amplification and typing of microsatellite loci where short DNA sequences are repeated a variable number of times. When applied to canine...
Touch DNA
Minute quantities of epithelial cells transferred by skin contact with a surface, without leaving a visible stain. Collected by swabbing contact points...
Anagen Phase
The actively growing phase of the hair follicle, during which the keratinocyte is in contact with the dermal papilla capillary and incorporates...
Biological Evidence
Any material of biological origin recovered in a forensic context that can yield information relevant to an investigation. Includes blood, semen, saliva,...
Canine STR Multiplex
A validated set of STR loci used to generate a genotypic profile from dog DNA. The International Society for Animal Genetics (ISAG)...
Cementum
A thin, bone-like mineralised tissue that covers the external surface of the tooth root. Deposited incrementally throughout life in alternating translucent and...
Chromatin
The complex of nuclear DNA wound around histone proteins in the nucleus. In forensic DNA extraction, chromatin must be disrupted to release...

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