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MC-ICP-MS (Multi-Collector Inductively Coupled Plasma Mass Spectrometry)

Definition

An instrument that ionises a liquid or laser-ablated sample in an argon plasma at about 8,000 K and simultaneously collects multiple ion beams. Faster throughput than TIMS and capable of measuring a wide range of elements, including those difficult to ionise on a filament.

Plasma temperature
About 8,000 K, argon plasma
Detector design
Multiple ion beams collected simultaneously
Sample introduction
Liquid or laser-ablated
Compared to TIMS
Faster throughput, wider element range

Common questions

Why choose MC-ICP-MS over TIMS for a forensic provenance case?+

TIMS requires elements that ionise readily on a heated filament, which excludes many elements of interest, while the plasma source in MC-ICP-MS ionises a much broader range of elements and processes samples faster, at some cost in precision for certain isotope systems.

What does laser-ablation sample introduction add?+

It allows isotope measurement directly from a solid sample surface, such as a small fragment of glass, metal, or bone, avoiding the dissolution step needed for liquid introduction and preserving spatial information within the sample.

Related terms

Delta Notation (δ)
A notation expressing the isotope ratio of a sample relative to an international standard in parts per thousand (per mil, ‰). Positive...
Epsilon Notation (ε)
Similar to delta but expressed in parts per ten thousand, used for radiogenic systems where variation is very small. Epsilon Nd and...
Radiogenic Isotope
An isotope produced by radioactive decay of a parent nuclide over geological time. Its abundance in a rock or mineral increases predictably...
Stable Isotope
An isotope that does not undergo radioactive decay. Ratios of stable isotopes change only through physical or biological fractionation, such as evaporation...
TIMS (Thermal Ionisation Mass Spectrometry)
An instrument that ionises a sample deposited on a metal filament and measures ion beam intensities with Faraday collectors. The gold standard...

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