LOD and LOQ
Definition
Limit of detection is three times the SD of blank or S/N of 3:1. Limit of quantitation is ten times SD of blank or S/N of 10:1. Below LOD: 'not detected'. Between LOD and LOQ: 'detected, below LOQ' rather than a number.
Related terms
- Accuracy and Precision
- Accuracy is closeness to the true value, measured as recovery from a spiked CRM with the 80 to 120 percent window. Precision...
- Control Chart
- Time-series plot of a QC measurement with warning limits at ±2σ and action limits at ±3σ from validation data. Patterns such as...
- Measurement Uncertainty (MU)
- A quantified parameter associated with a result that characterises the dispersion of values reasonably attributable to the measurand. Estimated by the GUM...
- Method Validation
- The process of demonstrating that an analytical method does what it claims: that it correctly identifies the target analyte, at what sensitivity,...
- Proficiency Testing (PT)
- A quality assurance mechanism in which laboratories analyse blind samples distributed by an external scheme coordinator and have their results compared against...
Explained in
- Method Validation, Measurement Uncertainty and Proficiency TestingLimit of detection is three times the SD of blank or S/N of 3:1. Limit of quantitation is ten times SD of blank or S/N of 10:1. Below LOD: 'not detected'. Betw...