Method validation
The documented process of demonstrating that an analytical method is fit for its intended purpose. Validation parameters: specificity, linearity (R² ≥ 0.995), accuracy (80-120% recovery), precision (intraday RSD < 5%, interday < 10%), robustness (Plackett-Burman screening), LOD (3σ/S:N 3:1), and LOQ (10σ/S:N 10:1).
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Related terms
Proficiency testing (PT)Accuracy and precisionControl chartCorrective action and CAPAENFSI (European Network of Forensic Science Institutes)ILAC MRA (International Laboratory Accreditation Cooperation Mutual Recognition Arrangement)ISO/IEC 17025:2017LOD and LOQManagement reviewMeasurement uncertaintyMeasurement uncertainty (MU)NABL (National Accreditation Board for Testing and Calibration Laboratories)