Lateral-flow immunochromatographic strip
Definition
A point-of-care format immunoassay in which a sample migrates along a nitrocellulose membrane past a labelled antibody zone and a capture antibody line. A visible band at the test line confirms the target antigen. Used for PSA detection in forensic triage because results appear within ten minutes without laboratory equipment.
Related terms
- Alpha-amylase (salivary isoform)
- An enzyme present in saliva at concentrations several orders of magnitude higher than in other body fluids. Detected immunologically using anti-human salivary...
- Inhibition agglutination assay
- A serological technique for detecting soluble antigens in body-fluid extracts. Known antibody is incubated with the stain extract; if the target antigen...
- Prostate-specific antigen (PSA)
- A serine protease glycoprotein (also called p30) secreted in high concentrations by the prostate gland into seminal plasma. The primary immunological marker...
- Secretor
- An individual whose ABO blood group antigens are expressed on red blood cells and also released into body fluids such as saliva,...
- Sexual assault forensic examination (SAFE) kit
- The standardised collection kit used by trained healthcare providers to obtain biological samples from a survivor within a defined collection window, typically...
Explained in
- Immunological Methods in Sexual Assault InvestigationsA point-of-care format immunoassay in which a sample migrates along a nitrocellulose membrane past a labelled antibody zone and a capture antibody line. A visi...