Skip to content

Cytochrome B (Cyt B)

Definition

A mitochondrial protein-coding gene widely used in forensic species identification before COI barcoding was standardised. Still used because its reference database for vertebrates is extensive and well-curated. Short-amplicon cyt b assays target fragments under 200 base pairs for use with degraded samples.

Related terms

16S rRNA
The small-subunit ribosomal RNA gene in bacteria (~1,550 bp). The V3-V4 hypervariable region (~470 bp) is amplified with universal bacterial primers for...
BOLD Systems
Barcode of Life Data System (University of Guelph, Canada). Holds over 9 million COI reference barcodes linked to voucher specimens, with mandatory...
Chain of Custody
The documented chronological record of who collected, handled, transferred, and examined a piece of evidence. For digital evidence, chain of custody includes...
CITES Appendix
CITES classifies listed species into three appendices. Appendix I prohibits commercial trade; Appendix II permits trade only with documented permits and quota...
COI (COX1)
Cytochrome-c oxidase subunit I gene. The 658-base-pair Folmer fragment is the globally adopted barcode-of-life marker for animals, curated in BOLD Systems and...
DNA Barcoding
Species identification using a short, standardised region of the mitochondrial genome. For animals, the primary barcode marker is a 648-base-pair segment of...
ITS Region
Internal transcribed spacer region, flanking the 5.8S rRNA gene between the 18S and 28S subunits in fungi and plants. The ITS1-5.8S-ITS2 fragment...
Mitochondrial DNA (mtDNA)
DNA located in mitochondria rather than the cell nucleus. Present in hundreds to thousands of copies per cell, making it recoverable from...
PCR-RFLP
PCR followed by restriction fragment length polymorphism analysis. A restriction enzyme cuts the amplicon at species-specific recognition sites; the resulting fragment pattern...
SILVA
Curated ribosomal RNA sequence database (Max Planck Institute for Marine Microbiology, Bremen). Provides quality-filtered 16S, 18S, 23S, and 28S reference alignments for...
STR Profiling
Short tandem repeat profiling: the same multi-locus PCR-based method used for human identity testing, adapted for target species with species-specific primer sets....

Explained in these topics

Your journey to becoming a forensic professional starts here.

Practice with mock tests, learn from structured notes, and get your questions answered by a global forensic community, all in one place.