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6-monoacetylmorphine (6-MAM)

A transient diagnostic metabolite of heroin (diacetylmorphine) formed by the rapid hydrolysis of one acetyl group. Half-life is 6 to 25 minutes in blood. Identification of 6-MAM in any matrix proves heroin exposure and excludes pharmaceutical morphine or codeine as the source.

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Related terms

Marquis reagent4-Anilinopiperidine scaffoldAlkaloid ratio profilingBenzoylecgonineBenzoylecgonine (BE)CarfentanilDiacetylmorphineDose heterogeneityDuquenois-Levine testMRM (multiple reaction monitoring)Narcotic (NDPS sense)NDPS commercial quantity

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