Transcript
Definition
An RNA molecule produced from a DNA template through transcription. Exons can remain in mature transcripts and can contain coding or untranslated sequence. Not every exon directly encodes protein. Changes in transcript abundance or structure also require assay-specific interpretation.
- Context
- Gene expression
For example, detecting a selected RNA product requires interpretation of assay performance and tissue context rather than assuming a unique body-fluid source.
Related terms
- Antiparallel
- Antiparallel describes the opposite directional orientations of paired nucleic-acid strands: one runs 5-prime to 3-prime while the other runs oppositely. Recognising that...
- Degradation Index
- A ratio or combination of RNA abundance measurements designed to capture the state of degradation of a sample. Often calculated as the...
- Nucleotide
- A nucleotide is a molecular building block containing a base, a sugar and phosphate-related structure. DNA and RNA contain different sugars and...
- Reverse Complement
- Complementary sequence written in the opposite strand’s usual 5-prime to 3-prime direction. Writing a reverse complement requires both complementary bases and reversal...
Explained in
- Nucleic Acids: Structure and FunctionAn RNA molecule produced by transcription.