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STR Profile

Definition

Short tandem repeat profile: the numerical representation of repeated DNA sequences at a defined set of loci, used to generate a forensic match statistic. Profiles contain no information about physical traits or health from the loci used forensically.

Marker type
Short tandem repeat
Output
Numerical repeat counts per locus
Phenotype data
None from forensic loci
Use
Identity comparison and database search

Common questions

Why can't an STR profile reveal appearance or health?+

The loci chosen for forensic panels sit in non-coding regions selected for variability, not for linkage to genes controlling traits or disease, so the profile carries no phenotype information even though it reliably distinguishes individuals.

How is a match statistic generated from the profile?+

Allele frequencies at each locus, drawn from population databases, are combined across the profile's loci to calculate the random match probability, the figure quoted in court as the statistical weight of a comparison.

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