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Speciation

Definition

Determining the chemical form of a metal in a sample, not just the total. Critical for arsenic because As(III) trivalent arsenite is 60 times more toxic than As(V) pentavalent arsenate, and methylated organic species like arsenobetaine from seafood are essentially non-toxic. Modern speciation runs by HPLC-ICP-MS.

Related terms

Bhasma
Calcined heavy-metal preparation in classical ayurvedic and siddha pharmacopoeia. Includes naga bhasma (lead), parad bhasma (mercury), tamra bhasma (copper). Heavy metals are...
Chelation Therapy
Administration of a polydentate ligand that forms a stable water-soluble complex with the metal cation and increases urinary excretion. BAL (dimercaprol) is...
Marsh Test
Sensitive 1836 method for arsenic in which the acidified sample is added to zinc and dilute sulphuric acid. The evolved arsine gas...
Mees Lines
Transverse white bands across the fingernails that follow acute or repeated chronic exposure to arsenic, thallium or selenium. Appear 4 to 8...
Reinsch Test
Classical screen for arsenic, antimony, mercury and bismuth. A clean copper strip is immersed in the acidified sample (concentrated HCl, near-boiling) for...

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