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Semiconservative Replication

Definition

Copying in which each daughter DNA duplex contains a parental strand and a newly synthesised strand. The principle describes replication, not an inference of who contributed forensic material. Identification requires appropriate variable markers and interpretation.

Context
DNA copying

For example, each daughter DNA duplex retains one parental strand rather than containing two wholly newly made strands under the stated replication model.

Related terms

Frameshift
A shift in a coding reading frame caused by a length change not divisible by three. A mismatch concerns a non-standard base...
Germline Mutation
A sequence change in a lineage that can contribute to offspring. A somatic mutation occurs in a body-cell lineage and is usually...
Somatic Mutation
A change occurring in a body-cell lineage, usually not transmitted to offspring. The category does not by itself identify the timing, cause...
Stutter
An amplification artefact at an STR target, commonly differing by one repeat from an allele. Dropout concerns a true contributor allele not...

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