Ribosome-Inactivating Protein (RIP)
Definition
A glycoprotein toxin that enzymatically depurinates 28S rRNA and shuts down protein synthesis. Abrin (Abrus precatorius) and ricin (Ricinus communis) are type 2 RIPs and are lethal in microgram quantities by parenteral routes.
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Explained in
- Plant Poisons of Medico-Legal Importance in IndiaA glycoprotein toxin that enzymatically depurinates 28S rRNA and shuts down protein synthesis. Abrin (Abrus precatorius) and ricin (Ricinus communis) are type...