PMN (Polymorphonuclear Neutrophil) Infiltration
Definition
The first histological cellular marker of antemortem vital reaction. Begins emigrating from wound-margin venules within 1-2 hours of injury; histologically visible at 6-12 hours; dense band present at 12-24 hours.
Related terms
- Agonal Period
- The final period of physiological life between loss of consciousness and cardiac arrest. Injuries inflicted in this period are legally antemortem but...
- Fibronectin
- Glycoprotein deposited in wound matrix within 12-24 hours of antemortem injury. Detectable by immunostaining; serves as an intermediate-stage vital-reaction marker when PMN...
- Histamine Vital-Reaction Marker
- Biochemical indicator released from mast cells within minutes of tissue injury. A 50% or greater histamine elevation at the wound margin versus...
- Perimortem Window
- The brief interval before and immediately after cardiac arrest in which injuries may be inflicted during life but produce absent or minimal...
- Vital Reaction
- The suite of physiological responses to tissue injury that require a functioning cardiovascular and cellular metabolism to occur: haemorrhage, neutrophil infiltration, vasoactive...
Explained in
- Antemortem vs Post-Mortem Injury DistinctionThe first histological cellular marker of antemortem vital reaction. Begins emigrating from wound-margin venules within 1-2 hours of injury; histologically vis...