Osteoclast
The large, multinucleated bone-resorbing cell responsible for excavating the resorption tunnel in a BMU. Activated by the RANKL/OPG cytokine axis. Creates the space that osteoblasts subsequently fill with new lamellar bone.
The large, multinucleated bone-resorbing cell responsible for excavating the resorption tunnel in a BMU. Activated by the RANKL/OPG cytokine axis. Creates the space that osteoblasts subsequently fill with new lamellar bone.
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