Isoallele

Two STR alleles that share the same repeat count (and therefore appear as the same allele on CE) but differ by a single nucleotide within the repeat sequence. MPS resolves isoalleles; CE does not. Resolution of isoalleles increases the discrimination power of the DNA profile.

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NGS Data Analysis: Allele Calling, Variant Callers and Quality Filters

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Isoallele

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