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Forensic Toxicology

Definition

The branch of toxicology that applies analytical chemistry, pharmacology and pathology to medico-legal questions, principally the detection, identification and quantitation of poisons, drugs and their metabolites in biological samples drawn at autopsy or from a living suspect or victim. The output is a written report admissible in an Indian court under Section 39 of the Bharatiya Sakshya Adhiniyam 2023.

Combines
Analytical chemistry, pharmacology, pathology
Detects
Poisons, drugs and metabolites in biological samples
Sample sources
Autopsy specimens, living suspects or victims
India admissibility
Section 329, Bharatiya Nagarik Suraksha Sanhita 2023 (govt scientific expert reports)

Common questions

Why does forensic toxicology need pharmacology and pathology alongside chemistry?+

Detecting a substance chemically is not enough; pharmacology explains how the dose and timing relate to the observed effects, and pathology relates any findings to the physical state of the body, together supporting a defensible interpretation rather than a bare detection result.

What distinguishes a toxicology report on a living subject from a postmortem one?+

A living-subject report typically addresses current impairment or exposure at the time of sampling, while a postmortem report must also account for redistribution of drugs after death and decomposition effects that can alter measured concentrations.

Related terms

Ante-Mortem vs Post-Mortem Sample
Antemortem samples are drawn from a living patient (most often blood, urine and gastric lavage at hospital admission); postmortem samples are collected...
BSA Section 63 Certification
The provision under the Bharatiya Sakshya Adhiniyam 2023 that governs admission of expert opinion. A forensic toxicology report carries the signature of...
Poison
Paracelsus framed the working definition in 1538 as 'sola dosis facit venenum', the dose alone makes the poison. Any substance, including water...
Presumptive vs Confirmatory Test
A presumptive test (Reinsch for heavy metals, Marquis for opioids, Trinder for salicylates) is fast, cheap and class-specific, used to triage caseloads....
Viscera
The standard set of organs and fluids collected at a suspected poisoning autopsy in India: stomach with contents, a length of upper...

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