External Validation
Definition
Assessment on independent material relevant to the intended application. Instruments, specimen types and operating conditions can differ. Success on a convenient dataset does not guarantee casework performance. Explain material differences rather than treating every external sample as equivalent validation.
- Context
- Method evaluation
For example, evaluating a method on independently collected relevant specimens provides a stronger test of generalisation than reusing material involved in tuning it.
Related terms
- Marker-Gene Profiling
- Targeted analysis of selected genetic marker regions to describe taxonomic composition under a stated method. Marker profiling examines selected taxonomic regions within...
- Microbiota
- Microorganisms associated with a specified environment or host site. Marker profiling examines selected taxonomic regions within a microbial community. Sampling, extraction, primers...
- Shotgun Metagenomics
- Sequencing all DNA in a sample rather than just the 16S amplicon. Provides taxonomic resolution beyond 16S and can characterise viruses and...
- Thanatomicrobiome
- The thanatomicrobiome describes microbial communities associated with a body after death, with usage often emphasising internal tissues. The sampled site, analytical method...