Depurination
Hydrolytic loss of a purine base (adenine or guanine) from the deoxyribose sugar, creating an abasic site that blocks DNA polymerase extension. One of the primary mechanisms of DNA degradation in aged biological evidence.
Hydrolytic loss of a purine base (adenine or guanine) from the deoxyribose sugar, creating an abasic site that blocks DNA polymerase extension. One of the primary mechanisms of DNA degradation in aged biological evidence.
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