Bombay Phenotype (Oh)
Definition
A rare phenotype in which individuals lack functional H antigen on red cells and in secretions due to mutations in FUT1 (and FUT2). Bombay individuals type serologically as group O but produce anti-H antibodies and are incompatible with all ABO-typed blood, including O.
Related terms
- ABO Transferase
- A glycosyltransferase enzyme encoded by the ABO gene on chromosome 9. The A allele encodes an enzyme that adds N-acetylgalactosamine to H...
- Forward Grouping (Cell Grouping)
- The direct test of red blood cells with known anti-A and anti-B reagent antibodies to determine which ABO antigens are present on...
- H Antigen
- A fucose-containing oligosaccharide on red cell surfaces and secreted epithelial cells, produced by FUT1 (on red cells) and FUT2 (in secretions). It...
- Reverse Grouping (Serum Grouping)
- Testing a person's serum against known A1 and B reagent red cells to identify which antibodies are present. A healthy adult with...
- Secretor Status
- A genetic trait that determines whether a person expresses their ABO blood group antigens in secreted body fluids such as saliva, semen,...
Explained in
- The ABO Blood Group System: Genetics and SerologyA rare phenotype in which individuals lack functional H antigen on red cells and in secretions due to mutations in FUT1 (and FUT2). Bombay individuals type ser...