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HemaTrace ABAcard

Definition

A lateral-flow device from Abacus Diagnostics that uses an anti-human haemoglobin monoclonal antibody. It is the most widely validated immunological blood confirmatory test in forensic literature. A positive result (test line visible plus control line visible) confirms human haemoglobin is present.

Related terms

Cross-reactivity
The capacity of an antibody raised against one analyte to bind structurally related compounds. In RIA, cross-reactivity is the main driver of...
Lateral-flow immunochromatographic assay
A rapid, single-use immunoassay format in which sample extract migrates along a nitrocellulose membrane past a detection zone loaded with antigen-specific antibody...
Monoclonal antibody
An antibody produced from a single B-cell clone, recognising a single specific epitope. In forensic species identification, monoclonal antibodies offer higher specificity...
Prozone (hook) effect
A false-negative agglutination result caused by antibody excess. When antibody molecules outnumber antigen sites, each site is occupied by a single antibody...
RSID-Blood
Rapid Stain Identification of Blood, a lateral-flow strip from Independent Forensics that also targets human haemoglobin. Functionally equivalent to HemaTrace in principle;...

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