Mass Spectrometry: Principles, Spectra Interpretation and Hyphenated Techniques (UGC-NET Unit II)

Advanced UGC-NET Forensic Science Unit II drill on mass spectrometry: ionisation modes (EI, CI, ESI, APCI, MALDI), mass analysers (quadrupole, ion trap, TOF, Orbitrap, FT-ICR), tandem MS (Q-TOF, triple quadrupole, MRM), spectral interpretation (molecular ion identification, isotope patterns, alpha cleavage, McLafferty rearrangement, sigma bond cleavage), accurate-mass formula calculation, hyphenated technique selection (GC-MS, LC-MS, ICP-MS, IR-MS), SWGDRUG identification criteria, and IUPAC recommendations. Hard-band scenario questions test which ionisation, analyser, transition, or fragmentation pathway applies in a real forensic toxicology, drugs of abuse, or trace evidence problem.