Proteolysis
Definition
Proteolysis is cleavage of peptide bonds in proteins or peptides through protease activity. It can occur in biological processes or during sample preparation, and its consequences depend on the target, conditions and subsequent analytical method rather than simply indicating general decomposition.
Related terms
- Allozyme
- An allelic enzyme variant, distinct from the broader category of isoenzymes. Allozymes are enzyme variants associated with alternative alleles at a locus....
- Denaturation
- Denaturation is disruption of a biological molecule’s usual structure under specified conditions. In PCR, it separates paired DNA strands sufficiently for subsequent...
- Immunoassay
- An assay using antigen–antibody recognition under specified conditions. Fluorescent responses can also decrease through interactions described as quenching. A signal change is...
- Pseudoperoxidase Activity
- Peroxide-dependent oxidation chemistry associated with haem proteins such as haemoglobin. Some screening reactions use haem-associated peroxide chemistry to reveal areas compatible with...
Explained in
- Proteins and Enzymes in Biological EvidenceCleavage of peptide bonds by proteases.