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Post-mortem genetic testing (cardiac)

Gene-panel analysis of post-mortem tissue (frozen fresh myocardium or paraffin-embedded blocks) targeting ion-channel and cardiomyopathy genes. Recommended in the UK (RCPath inherited cardiac conditions protocol), Australia (NHFA sudden-death guidelines), and internationally for unexplained SCD in individuals under 40 to enable familial cascade screening.

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Related terms

ARVC (arrhythmogenic right ventricular cardiomyopathy)ChannelopathyHypertrophic cardiomyopathy (HCM)Serum tryptaseSIDS (Sudden Infant Death Syndrome)Sudden cardiac death (SCD)Triple-risk model (SIDS)

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