Phenotype frequency
Definition
The proportion of a given population that expresses a particular antigen combination. Multiplying phenotype frequencies across independent loci gives the combined frequency of a multi-system profile, which is the key statistic in blood group evidence.
Related terms
- Absorption-elution
- A technique for detecting antigens on dried red cell debris. Specific antiserum is absorbed onto the stain; if the antigen is present,...
- Antiserum
- Serum collected from an immunised animal containing antibodies directed against a specific antigen or group of antigens. In species identification, antiserum raised...
- Blood group system
- A set of red cell surface antigens encoded by one gene locus or by two tightly linked loci. The International Society of...
- Linkage disequilibrium
- The non-random association of alleles at different loci within a population. Certain HLA allele combinations (e.g., HLA-A1 with HLA-B8 with HLA-DR3) occur...
- Probability of exclusion
- The proportion of the population whose blood type differs from that of the stain and who would therefore be excluded as its...
Explained in
- Minor Blood Group Systems: MNS, Kell, Duffy, and OthersThe proportion of a given population that expresses a particular antigen combination. Multiplying phenotype frequencies across independent loci gives the combi...